H2N2V1, Main, Exploration, bibRecord, 002302

INFLUENZA B IN HOUSEHOLDS: VIRUS SHEDDING WITHOUT SYMPTOMS OR ANTIBODY RESPONSE

Identifieur interne : 002302 ( Main/Exploration ); précédent : 002301; suivant : 002303

INFLUENZA B IN HOUSEHOLDS: VIRUS SHEDDING WITHOUT SYMPTOMS OR ANTIBODY RESPONSE

Auteurs : Hjordis M. Foy [États-Unis] ; Marion K. Cooney ; Inez D. Allan ; Janice K. Albrecht

Source :

American Journal of Epidemiology [ 0002-9262 ] ; 1987.

RBID : ISTEX:FC1649E9D11E4FB9EC7D9EAC3FC6AE76BDE54ADB

Abstract

Foy, H. M. (Dept. of Epidemiology, U. of Washington, Seattle, WA 98195), M. K. Cooney, I. D. Allan, and J. K. Albrecht. Influenza B in households: virus shedding without symptoms or antibody response. Am J Epidemiol 1987;126:506–15. In the fall of 1983, 53 households were enrolled in a double-blind trial of alpha2 interferon as an intranasal spray to prevent common colds. During the winter/spring of 1984, 26 households were infected with influenza type B, as shown by isolation of the virus (19 households) and/or significant antibody titer rises (seven households). Interferon did not prevent influenza B infection or modify resulting illness. Of 37 persons shedding virus, 12 were asymptomatic. All were older than age 12 years, and 10 did not respond with antibody by any of the five test methods employed (complement fixation, hemagglutination inhibition, enzyme-linked immunosorbent assay (ELISA), neutralization, and Western blot). In contrast, of 13 symptomatic persons shedding virus from whom sera were available, 11 had significant antibody titer rises. Infection rates were highest among teenagers, but also surprisingly high among the 11 persons observed who were aged 50 years or older, four of whom were infected. The case-to-case interval in household transmission varied between one and nine days. Longer intervals of one, two, and four months between infections among family members were also observed, suggesting repeated introductions. Neither virus isolation alone nor serologic tests was sufficient to estimate infection rates.

Url:

https://api.istex.fr/ark:/67375/HXZ-XR4H08M6-Z/fulltext.pdf

DOI: 10.1093/oxfordjournals.aje.a114683

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Istex, to step Corpus: 001511
to stream Istex, to step Curation: 001511
to stream Istex, to step Checkpoint: 001004
to stream Main, to step Merge: 002413
to stream Main, to step Curation: 002302

Le document en format XML

<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>INFLUENZA B IN HOUSEHOLDS: VIRUS SHEDDING WITHOUT SYMPTOMS OR ANTIBODY RESPONSE</title>
<author><name sortKey="Foy, Hjordis M" sort="Foy, Hjordis M" uniqKey="Foy H" first="Hjordis M." last="Foy">Hjordis M. Foy</name>
</author>
<author><name sortKey="Cooney, Marion K" sort="Cooney, Marion K" uniqKey="Cooney M" first="Marion K." last="Cooney">Marion K. Cooney</name>
</author>
<author><name sortKey="Allan, Inez D" sort="Allan, Inez D" uniqKey="Allan I" first="Inez D." last="Allan">Inez D. Allan</name>
</author>
<author><name sortKey="Albrecht, Janice K" sort="Albrecht, Janice K" uniqKey="Albrecht J" first="Janice K." last="Albrecht">Janice K. Albrecht</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:FC1649E9D11E4FB9EC7D9EAC3FC6AE76BDE54ADB</idno>
<date when="1987" year="1987">1987</date>
<idno type="doi">10.1093/oxfordjournals.aje.a114683</idno>
<idno type="url">https://api.istex.fr/ark:/67375/HXZ-XR4H08M6-Z/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001511</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001511</idno>
<idno type="wicri:Area/Istex/Curation">001511</idno>
<idno type="wicri:Area/Istex/Checkpoint">001004</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001004</idno>
<idno type="wicri:doubleKey">0002-9262:1987:Foy H:influenza:b:in</idno>
<idno type="wicri:Area/Main/Merge">002413</idno>
<idno type="wicri:Area/Main/Curation">002302</idno>
<idno type="wicri:Area/Main/Exploration">002302</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">INFLUENZA B IN HOUSEHOLDS: VIRUS SHEDDING WITHOUT SYMPTOMS OR ANTIBODY RESPONSE</title>
<author><name sortKey="Foy, Hjordis M" sort="Foy, Hjordis M" uniqKey="Foy H" first="Hjordis M." last="Foy">Hjordis M. Foy</name>
<affiliation></affiliation>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Address reprint requests to Prof. Hjordis M. Foy, Department of Epidemiology, SC-36, University of Washington, Seattle</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Cooney, Marion K" sort="Cooney, Marion K" uniqKey="Cooney M" first="Marion K." last="Cooney">Marion K. Cooney</name>
<affiliation><wicri:noCountry code="subField">WA.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Allan, Inez D" sort="Allan, Inez D" uniqKey="Allan I" first="Inez D." last="Allan">Inez D. Allan</name>
<affiliation><wicri:noCountry code="subField">WA.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Albrecht, Janice K" sort="Albrecht, Janice K" uniqKey="Albrecht J" first="Janice K." last="Albrecht">Janice K. Albrecht</name>
<affiliation><wicri:noCountry code="subField">NJ.</wicri:noCountry>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j" type="main">American Journal of Epidemiology</title>
<idno type="eISSN">1476-6256</idno>
<idno type="ISSN">0002-9262</idno>
<imprint><publisher>Oxford University Press</publisher>
<date when="1987-09">1987</date>
<biblScope unit="vol">126</biblScope>
<biblScope unit="issue">3</biblScope>
<biblScope unit="page" from="506">506</biblScope>
<biblScope unit="page" to="515">515</biblScope>
</imprint>
<idno type="ISSN">0002-9262</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0002-9262</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract">Foy, H. M. (Dept. of Epidemiology, U. of Washington, Seattle, WA 98195), M. K. Cooney, I. D. Allan, and J. K. Albrecht. Influenza B in households: virus shedding without symptoms or antibody response. Am J Epidemiol 1987;126:506–15. In the fall of 1983, 53 households were enrolled in a double-blind trial of alpha2 interferon as an intranasal spray to prevent common colds. During the winter/spring of 1984, 26 households were infected with influenza type B, as shown by isolation of the virus (19 households) and/or significant antibody titer rises (seven households). Interferon did not prevent influenza B infection or modify resulting illness. Of 37 persons shedding virus, 12 were asymptomatic. All were older than age 12 years, and 10 did not respond with antibody by any of the five test methods employed (complement fixation, hemagglutination inhibition, enzyme-linked immunosorbent assay (ELISA), neutralization, and Western blot). In contrast, of 13 symptomatic persons shedding virus from whom sera were available, 11 had significant antibody titer rises. Infection rates were highest among teenagers, but also surprisingly high among the 11 persons observed who were aged 50 years or older, four of whom were infected. The case-to-case interval in household transmission varied between one and nine days. Longer intervals of one, two, and four months between infections among family members were also observed, suggesting repeated introductions. Neither virus isolation alone nor serologic tests was sufficient to estimate infection rates.</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Washington (État)</li>
</region>
</list>
<tree><noCountry><name sortKey="Albrecht, Janice K" sort="Albrecht, Janice K" uniqKey="Albrecht J" first="Janice K." last="Albrecht">Janice K. Albrecht</name>
<name sortKey="Allan, Inez D" sort="Allan, Inez D" uniqKey="Allan I" first="Inez D." last="Allan">Inez D. Allan</name>
<name sortKey="Cooney, Marion K" sort="Cooney, Marion K" uniqKey="Cooney M" first="Marion K." last="Cooney">Marion K. Cooney</name>
</noCountry>
<country name="États-Unis"><region name="Washington (État)"><name sortKey="Foy, Hjordis M" sort="Foy, Hjordis M" uniqKey="Foy H" first="Hjordis M." last="Foy">Hjordis M. Foy</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002302 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002302 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    H2N2V1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     ISTEX:FC1649E9D11E4FB9EC7D9EAC3FC6AE76BDE54ADB
   |texte=   INFLUENZA B IN HOUSEHOLDS: VIRUS SHEDDING WITHOUT SYMPTOMS OR ANTIBODY RESPONSE
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 14 19:59:40 2020. Site generation: Thu Mar 25 15:38:26 2021

	Serveur d'exploration H2N2
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration H2N2

INFLUENZA B IN HOUSEHOLDS: VIRUS SHEDDING WITHOUT SYMPTOMS OR ANTIBODY RESPONSE

INFLUENZA B IN HOUSEHOLDS: VIRUS SHEDDING WITHOUT SYMPTOMS OR ANTIBODY RESPONSE

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri